Since October is Domestic Violence Awareness Month, in addition to Breast Cancer Awareness Month, I thought I would mention House of Ruth of Maryland. I used to intern here, and it is a great organization. This charity idea follows the same vein as Bethesda House - a great way to clear out your apartment of items that you plan to register for. Sometimes they cannot accept used items, but it is possible that women moving out of the shelter might be interested in having those items so they can start a new life, so give them a call and ask.
This is also a really great place to take those gifts that are duplicates or are something you already own, so you don't really want them, but you really don't want to just give something brand new away to Goodwill and the person didn't give you a gift receipt. (If it's a close friend, don't donate their gift. If they are like me, they will nose around and ask if you found their gift useful. But usually your close friends won't get you something you already have or can't return.)
Go here to check out their current in-kind donations wish list - common items include twin bedsheets, bath towels and washcloths, plastic storage containers, bed pillows, household items such as plates, glassware, flatware, pots & pans, and toasters, and paper plates, etc. (maybe that you bought for a welcome picnic or day-after brunch and didn't use). Additionally, left over shower favors or prizes like lotions and toiletries, or those extra makeup products or brushes that you bought for your hair and makeup trials could all find a good home here.
If you are interested in giving a financial contribution, donate here. You could then include the usual donations cards at people places explaining where their donation went. It would also be a great thing to donate to in lieu of bridal shower favors. Shower favors are a little useless anyway, and as a frequent shower guest, I think I would appreciate it.